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Project information
Basic ketones and their derivatives as potential anti-infective and anti-tumor drugs

Project Identification
MUNI/IGA/0932/2021
Project Period
1/2022 - 12/2022
Investor / Pogramme / Project type
Masaryk University
  • Internal grant agency MU
MU Faculty or unit
Faculty of Pharmacy

This research focus on basic derivatives of aromatic-aliphatic ketones, especially thiosemicarbazone and semicarbazone derivatives of acetophenone and their therapeutic importance. Basic ketones and their derivatives containing an azomethine group exhibit a wide range of biological activities, including the widespread application of their metal complexes. This fact leads to the targeting of mentioned substances as potential inhibitors of aminopeptidase N and tyrosine kinase.

Publications

Total number of publications: 8

2023

2022

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