Basic ketones and their derivatives as potential anti-infective and anti-tumor drugs

Kód projektu
MUNI/IGA/0932/2021
Období řešení
1/2022 - 12/2022
Investor / Programový rámec / typ projektu
Masarykova univerzita
Fakulta / Pracoviště MU
Farmaceutická fakulta

This research focus on basic derivatives of aromatic-aliphatic ketones, especially thiosemicarbazone and semicarbazone derivatives of acetophenone and their therapeutic importance. Basic ketones and their derivatives containing an azomethine group exhibit a wide range of biological activities, including the widespread application of their metal complexes. This fact leads to the targeting of mentioned substances as potential inhibitors of aminopeptidase N and tyrosine kinase.

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