Department of Applied Pharmacy
Department of Natural Drugs
Department of Pharmaceutical Technology
Department of Applied Pharmacy has a wide scope from history through social to legal and economic directions. It emphasizes the provision of quality, efficacy, safety, and economic effectiveness of pharmacotherapy. Subjects such as the history of pharmacy, social pharmacy, pharmacy, law and ethics for pharmacists, industrial pharmacy, pharmaceutical care, medicinal registration, health care economics and others are taught at Department. In further educational and creative activities of Department addresses the issue of providing pharmaceutical and clinical-pharmaceutical care, pharmacoeconomic, legislation and ethics of pharmaceutical professional activities with an emphasis on ensuring the quality, efficacy, safety, and economic effectiveness of pharmacotherapy. An integral part is the historical development and present state of pharmacy and its social status.
Department of Natural Drugs research and study medicinal products and excipients of natural origin. It deals with the search for and study of their sources (plants, animals, inanimate nature), the possibilities of obtaining them, detection the content of active substances, their biosynthesis and mechanical effect and the possibilities of practical use. Subjects such as pharmacognosy, botany, toxicology of natural substances, production of medicinal plants or phytochemistry are taught at Department. The research activities of ÚPL focus on the isolation and identification of new substances from plant material and the determination of biological activity, eg their antioxidant ability or ability to influence the functioning of selected enzymes, as well as monitoring the production and biotransformation ability of tissue cultures of higher plants.
Pharmaceutical technology (pharmaceutics) is one of the science branches of general pharmacy. It envelops formulation, preparation, manufacturing, evaluation, safety guarding and other aspects connected to drug dosage forms. In this space you should get a glimpse of our main activities.
Department of Pharmacology and Toxicology
Department of Chemical Drugs
Department of Molecular Pharmacy
The Department of Pharmacology and Toxicology is focused on the effect of drugs on the human body up to the cellular and molecular level, the therapeutic use of drugs, their possible side effects and interactions. Subjects such as pharmacology, human physiology and pathophysiology, morphology, biology, pathology, toxicology and others are taught at the department. The research activity is focused on preclinical testing of new biologically active substances, especially in relation to tumor, endocrine and metabolic disorders and biological evaluation of potential hemostatics and new medical devices for wound care, in the clinical field on the effectiveness of pharmacotherapy and the occurrence of side effects of treatment.
Department of Chemical Drugs focuses on medicinal and excipient substances of synthetic origin, their synthesis and analytical control of their structures, studies the relationships between chemical structures and biological activities, as well as physicochemical, analytical and biochemical properties of potential or already used medicinal products. Subjects such as pharmaceutical chemistry, inorganic and organic chemistry, analytical chemistry, medicinal analysis and others are taught at Department. The research activities of Department focus on synthesis, control of the structures, study of physicochemical properties and analytical evaluation of new biological active substances especially in the field of neurodegenerative diseases, cardiovascular diseases, antitumor substances concretely focusing on inhibition of specific enzymes, antimicrobials, anti-inflammatory substances of natural origin and their analogues and substances affecting the passage of the drug through a skin barrier.
Department of Molecular Pharmacy works with tissue cultures, explants, and microorganisms, on which the biological activity of new substances of natural and synthetic origin is tested. Subjects such as molecular biology, microbiology, drug biotechnology, structural biology and proteomics are taught at the Department. The research activities of the Department focus on the determination of various biological activities of potentially active substances, namely antimicrobial, cytotoxic, antioxidant, anti-inflammatory and antidiabetic activities. There is also research in the field of molecular oncology and measurements of the toxicity of drugs to plants in the environment.