doc. RNDr. Jan Hošek, Ph.D.

Associate professor, Department of Molecular Pharmacy

Office: 310
Palackého třída 1946/1
612 00 Brno

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Phone:	+420 541 562 852
E‑mail:

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Basic information

Type

Total number of publications: 30

2023

Sildenafil affects the human Kir2.1 and Kir2.2 channels at clinically relevant concentrations: Inhibition potentiated by low Ba2+

IIJIMA Akimasa ŠVECOVÁ Olga HOŠEK Jan KULA Roman BÉBAROVÁ Markéta

Article in Periodical

FRONTIERS IN PHARMACOLOGY, year: 2023, volume: 14, edition: February 2023, DOI

2022

Inherited arrhythmias: from gene variants to ionic channel dysfunctions

BÉBAROVÁ Markéta ŠVECOVÁ Olga CHMELÍKOVÁ Larisa HOŠEK Jan PÁSEK Michal BÁRTA Tomáš PACHERNÍK Jiří SYNKOVÁ Iva NOVOTNÝ Tomáš

Year: 2022, type:
Translational research in the field of inherited arrhythmias

BÉBAROVÁ Markéta ŠVECOVÁ Olga CHMELÍKOVÁ Larisa ZELENÁK Štefan RADASZKIEWICZ Katarzyna Anna HOŠEK Jan PÁSEK Michal BÁRTA Tomáš SYNKOVÁ Iva NOVOTNÝ Tomáš

Conference abstract

Year: 2022, type: Conference abstract
Trifluoromethylcinnamanilide Michael Acceptors for Treatment of Resistant Bacterial Infections

STRHÁRSKY Tomáš PINDJAKOVA Dominika KOS Jiří VRABLOVA Lucia ŠMAK Pavel MICHNOVA Hana GONĚC Tomáš HOŠEK Jan ORAVEC Michal JENDRZEJEWSKA Izabela ČÍŽEK Alois JAMPILEK Josef

Article in Periodical

International Journal of Molecular Sciences, year: 2022, volume: 23, edition: 23, DOI

2021

Clinical, genetic and functional analysis of R562S-Kv7.1 mutation associated with long QT syndrome type 1

ŠVECOVÁ Olga KULA Roman CHMELÍKOVÁ Larisa HOŠEK Jan SYNKOVÁ Iva NOVOTNÝ Tomáš BÉBAROVÁ Markéta

Conference abstract

Year: 2021, type: Conference abstract
Dysfunkce na podkladě mutace R562S asociované se syndromem dlouhého QT typu 1

ŠVECOVÁ Olga KULA Roman CHMELÍKOVÁ Larisa HOŠEK Jan SYNKOVÁ Iva NOVOTNÝ Tomáš BÉBAROVÁ Markéta

Conference abstract

Year: 2021, type: Conference abstract

2020

Protizánětlivý potenciál kompozitů kvasinkových glukanových částic a geranylovaného flavonoidu diplakonu

ČERNA Lucie BAĎO Zuzana ŠALAMÚNOVÁ Petra ŠMEJKAL Karel HANUŠ Jaroslav HOŠEK Jan

Article in Periodical

Česká a slovenská farmacie, year: 2020, volume: 2020, edition: 69
Therapeutic potential of prenylated stilbenoid macasiamenene F through its anti-inflammatory and cytoprotective effects on LPS-challenged monocytes and microglia

LELÁKOVÁ Veronika BÉRAUD-DUFOUR Sophie HOŠEK Jan ŠMEJKAL Karel PRACHYAWARAKORN Vilailak PAILEE Phanruethai WIDMANN Catherine VÁCLAVÍK Jiří COPPOLA Thierry MAZELLA Jean BLONDEAU Nicolas HEURTEAUX Catherine

Article in Periodical

JOURNAL OF ETHNOPHARMACOLOGY, year: 2020, volume: 263, edition: 263, DOI

2019

Functional characteristics of mutations identified in patients with long QT syndrome type 1, T309I and R562S

BÉBAROVÁ Markéta ŠVECOVÁ Olga BAIAZITOVA Larisa POLICAROVÁ Marcela HOŠEK Jan NOVOTNÝ Tomáš

Conference abstract

Year: 2019, type: Conference abstract
Mutace T309I asociovaná se syndromem dlouhého QT typu 1: akumulace IKs jako mechanismus ochrany srdce proti arytmii

BÉBAROVÁ Markéta SYNKOVÁ Iva ANDRŠOVÁ Irena BAIAZITOVA Larisa ŠVECOVÁ Olga HOŠEK Jan PÁSEK Michal VÍT Pavel VALÁŠKOVÁ Iveta GAILLYOVÁ Renata NAVRÁTIL Rostislav NOVOTNÝ Tomáš

Conference abstract

Year: 2019, type: Conference abstract